PLK3 Antikörper (C-Term)
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- Target Alle PLK3 Antikörper anzeigen
- PLK3 (Polo-Like Kinase 3 (PLK3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PLK3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to PLK3.
- Aufreinigung
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PLK3.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PLK3 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- PLK3 (Polo-Like Kinase 3 (PLK3))
- Andere Bezeichnung
- PLK3 (PLK3 Produkte)
- Synonyme
- cnk antikoerper, wu:fi35f10 antikoerper, fnk antikoerper, prk antikoerper, plx3 antikoerper, MGC89507 antikoerper, PLK2/3 antikoerper, NV15469 antikoerper, Plx3 antikoerper, CNK antikoerper, FNK antikoerper, PRK antikoerper, Cnk antikoerper, Fnk antikoerper, polo-like kinase 3 (Drosophila) antikoerper, polo like kinase 3 antikoerper, polo-like kinase 3 antikoerper, polo-like kinase 3 S homeolog antikoerper, polo-like kinase 3 L homeolog antikoerper, Serine/threonine-protein kinase plk-3 antikoerper, plk3 antikoerper, PLK3 antikoerper, LOC100118436 antikoerper, plk3.S antikoerper, plk3.L antikoerper, Plk3 antikoerper, plk-3 antikoerper
- Hintergrund
- CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.Synonyms: CNK, Cytokine-inducible serine/threonine-protein kinase, FGF-inducible kinase, FNK, PRK, Polo-like kinase 3, Proliferation-related kinase, Serine/threonine-protein kinase PLK3
- Gen-ID
- 1263, 9606
- UniProt
- Q9H4B4
- Pathways
- Regulation of long-term Neuronal Synaptic Plasticity
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