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PLK3 Antikörper (C-Term)

PLK3 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB0875 unconjugated
Produktnummer ABIN392602
  • Target Alle PLK3 Antikörper anzeigen
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-646, C-Term
    Reaktivität
    • 50
    • 23
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 46
    • 2
    • 2
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLK3 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 34
    • 24
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-646 amino acids from the C-terminal region of human PLK3.
    Klon
    RB0875
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PLK3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Zhang, Shi, Paddon, Hampong, Dai, Pelech: "B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35726-34, (2004) (PubMed).

  • Target
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Andere Bezeichnung
    PLK3 (PLK3 Produkte)
    Synonyme
    cnk antikoerper, wu:fi35f10 antikoerper, fnk antikoerper, prk antikoerper, plx3 antikoerper, MGC89507 antikoerper, PLK2/3 antikoerper, NV15469 antikoerper, Plx3 antikoerper, CNK antikoerper, FNK antikoerper, PRK antikoerper, Cnk antikoerper, Fnk antikoerper, polo-like kinase 3 (Drosophila) antikoerper, polo like kinase 3 antikoerper, polo-like kinase 3 antikoerper, polo-like kinase 3 S homeolog antikoerper, polo-like kinase 3 L homeolog antikoerper, Serine/threonine-protein kinase plk-3 antikoerper, plk3 antikoerper, PLK3 antikoerper, LOC100118436 antikoerper, plk3.S antikoerper, plk3.L antikoerper, Plk3 antikoerper, plk-3 antikoerper
    Hintergrund
    CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.
    Molekulargewicht
    71629
    Gen-ID
    1263
    NCBI Accession
    NP_004064
    UniProt
    Q9H4B4
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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