FGF10 Antikörper (C-Term)

Produktnummer ABIN360398

Der Kaninchen Polyklonal Anti-FGF10-Antikörper wurde für EIA und IHC (p) validiert. Er ist geeignet, FGF10 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für FGF10 Antikörper (C-Term) (ABIN360398)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF10 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FGF10 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to FGF10.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGF10.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-FGF10 Antikörper (ABIN360398)

El Agha, Moiseenko, Kheirollahi, De Langhe, Crnkovic, Kwapiszewska, Kosanovic, Schwind, Schermuly, Henneke, MacKenzie, Quantius, Herold, Ntokou, Ahlbrecht, Morty, Günther, Seeger, Bellusci: "Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis." in: Cell stem cell, Vol. 20, Issue 2, pp. 261-273.e3, (2016) (PubMed).

Details zu FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF10

Hintergrund: FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.Synonyms: FGF-10, Fibroblast growth factor 10, KGF2, Keratinocyte growth factor 2

Gen-ID: 2255, 9606

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus