RND3 Antikörper (Middle Region)

Produktnummer ABIN360047

Der Kaninchen Polyklonal Anti-RND3-Antikörper wurde für IHC (p) und EIA validiert. Er ist geeignet, RND3 in Proben von Human zu detektieren.

Kurzübersicht für RND3 Antikörper (Middle Region) (ABIN360047)

Target: RND3 (rho Family GTPase 3 (RND3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RND3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-RND3 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody reacts to ARHE.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human AEHE.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Andere Bezeichnung: RND3 / ARHE

Hintergrund: Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925), GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855), and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE

Gen-ID: 390, 9606

UniProt: P61587