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LMTK2 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LMTK2 in IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN359287

Kurzübersicht für LMTK2 Antikörper (N-Term) (ABIN359287)

Target

Alle LMTK2 Antikörper anzeigen
LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Reaktivität

  • 25
  • 1
Human

Wirt

  • 23
  • 1
  • 1
Kaninchen

Klonalität

  • 24
  • 1
Polyklonal

Konjugat

  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LMTK2 Antikörper ist unkonjugiert

Applikation

  • 17
  • 13
  • 11
  • 4
  • 4
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody reacts to LMTK2.

    Aufreinigung

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LMTK2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

    Andere Bezeichnung

    LMTK2

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: AATYK2, Apoptosis-associated tyrosine kinase 2, BREK, Brain-enriched kinase, CDK5/p35-regulated kinase, CPRK, EC=2.7.11.1, KIAA1079, KPI2, Kinase/phosphatase/inhibitor 2, LMR2, LMTK2, Lemur tyrosine kinase 2, Serine/threonine protein kinase KPI-2, Serine/threonine-protein kinase LMTK2

    Gen-ID

    22853, 9606

    UniProt

    Q8IWU2

    Pathways

    RTK Signalweg, Neurotrophin Signalübertragung
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