ADK Antikörper (N-Term)

Produktnummer ABIN359195

Produktdetails anti-ADK Antikörper

Target: ADK (Adenosine Kinase (ADK))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ADK.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ADK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ADK

Target: ADK (Adenosine Kinase (ADK))

Andere Bezeichnung: Adenosine Kinase (AK) (ADK Produkte)

Synonyme: AK antikoerper, ADK antikoerper, DDBDRAFT_0186795 antikoerper, DDBDRAFT_0230174 antikoerper, DDB_0186795 antikoerper, DDB_0230174 antikoerper, ATPADK1 antikoerper, F3G5.4 antikoerper, F3G5_4 antikoerper, adenosine kinase antikoerper, adk antikoerper, 2310026J05Rik antikoerper, 5033405D03Rik antikoerper, AI255373 antikoerper, AI987814 antikoerper, Ak antikoerper, adenosine kinase antikoerper, ATP:adenosine 5'-phosphotransferase antikoerper, Adenosine kinase antikoerper, adenosine kinase S homeolog antikoerper, ADK antikoerper, adk antikoerper, Adk antikoerper, CNN02130 antikoerper, LOC5572668 antikoerper, CMU_026370 antikoerper, adk.S antikoerper

Hintergrund: Adenosine kinase (ATP:adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well-characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Animal studies have demonstrated that a deficiency of adenosine metabolism a powerful contributor to the development of neonatal hepatic steatosis, providing a model for the rapid development of postnatally lethal fatty liver.Synonyms: ADK, Adenosine 5'-phosphotransferase

Gen-ID: 132, 9606

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process