Aurora Kinase C Antikörper (N-Term)

Produktnummer ABIN359035

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Aurora Kinase C in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Aurora Kinase C Antikörper (N-Term) (ABIN359035)

Target: Aurora Kinase C (AURKC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-Aurora Kinase C Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognizes Aurora-C.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of Human Aurora-C. Genename: AURKC

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunofluorescence: 1/100-1/500. Not Suitable for Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Andere Bezeichnung: Aurora Kinase C

Hintergrund: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.Synonyms: AIE2, AIK3, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 2, STK13, Serine/threonine-protein kinase 13

Molekulargewicht: 35591 Da

Gen-ID: 6795, 9606

UniProt: Q9UQB9

Pathways: Zellzyklus, Maintenance of Protein Location