SPPL2A Antikörper (N-Term)

Produktnummer ABIN358852

Produktdetails anti-SPPL2A Antikörper

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPPL2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to SPPL2a.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SPPL2a.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu SPPL2A

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Andere Bezeichnung: SPPL2A (SPPL2A Produkte)

Synonyme: RGD1563001 antikoerper, SPPL2A antikoerper, LOC453430 antikoerper, LOC100231183 antikoerper, IMP3 antikoerper, PSL2 antikoerper, 2010106G01Rik antikoerper, C130089K23Rik antikoerper, signal peptide peptidase-like 2A antikoerper, signal peptide peptidase like 2A antikoerper, Signal peptide peptidase-like 2A antikoerper, Sppl2a antikoerper, SPPL2A antikoerper, sppl2a antikoerper, psl2 antikoerper

Hintergrund: By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.Synonyms: IMP-3, IMP3, Intramembrane protease 3, PSL2, Presenilin-like protein 2, SPP-like 2A, Signal peptide peptidase-like 2A

Gen-ID: 84888, 9606

UniProt: Q8TCT8