MMP24 Antikörper (Middle Region)

Produktnummer ABIN358694

Der Kaninchen Polyklonal Anti-MMP24-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, MMP24 in Proben von Human zu detektieren.

Kurzübersicht für MMP24 Antikörper (Middle Region) (ABIN358694)

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-MMP24 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody reacts top MMP24.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MMP24.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MMP24

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Andere Bezeichnung: MMP-24

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).Synonyms: MMP24, MT-MMP 5, MT5-MMP, MT5MMP, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5

Gen-ID: 10893, 5874

UniProt: Q9Y5R2