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MMP24 Antikörper (N-Term)

MMP24 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044304
  • Target Alle MMP24 Antikörper anzeigen
    MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))
    Bindungsspezifität
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-225, N-Term
    Reaktivität
    • 32
    • 15
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 32
    • 1
    Kaninchen
    Klonalität
    • 32
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MMP24 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 8
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Matrix metalloproteinase-24(MMP24) detection. Tested with WB in Human,Mouse,Rat.
    Sequenz
    YHEIKSDRKE ADIMIFFA
    Kreuzreaktivität (Details)
    Predicted Cross Reactivity: mouse, rat
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Matrix metalloproteinase-24(MMP24) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: matrix metallopeptidase 24(membrane-inserted)
    Protein Name: Matrix metalloproteinase-24
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24(208-225aa YHEIKSDRKEADIMIFFA), identical to the related mouse and rat sequences.
    Isotyp
    IgG
    Top Product
    Discover our top product MMP24 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

    Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." in: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

  • Target
    MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))
    Andere Bezeichnung
    MMP24 (MMP24 Produkte)
    Synonyme
    MMP-24 antikoerper, MMP25 antikoerper, MT-MMP 5 antikoerper, MT-MMP5 antikoerper, MT5-MMP antikoerper, MT5MMP antikoerper, MTMMP5 antikoerper, AU040325 antikoerper, Mt5-mmp antikoerper, si:ch211-239j9.5 antikoerper, MMP24 antikoerper, mt3-mmp antikoerper, matrix metallopeptidase 24 antikoerper, matrix metallopeptidase 16 S homeolog antikoerper, MMP24 antikoerper, Mmp24 antikoerper, mmp24 antikoerper, mmp16.S antikoerper
    Hintergrund
    Matrix metalloproteinase-24, also known as MT5MMP or MMP25, is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP(MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. This gene may be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.

    Synonyms: Matrix metallopeptidase 24(membrane inserted) antibody|Matrix metallopeptidase 24 antibody|Membrane type 5 matrix metalloproteinase antibody|Membrane type matrix metalloproteinase 5 antibody|Membrane-type matrix metalloproteinase 5 antibody|Membrane-type-5 matrix metalloproteinase antibody|MMP 24 antibody|MMP 25 antibody|MMP-24 antibody|Mmp24 antibody|MMP24_HUMAN antibody|MMP25 antibody|MT MMP5 antibody|MT-MMP 5 antibody|MT5 MMP antibody|MT5-MMP antibody|MT5MMP antibody|MTMMP5 antibody|Processed matrix metalloproteinase-24 antibody
    UniProt
    Q9Y5R2
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