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MMP17 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MMP17 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN358690

Kurzübersicht für MMP17 Antikörper (Middle Region) (ABIN358690)

Target

Alle MMP17 Antikörper anzeigen
MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität

  • 47
  • 33
  • 10
  • 1
  • 1
Human

Wirt

  • 59
  • 4
Kaninchen

Klonalität

  • 51
  • 12
Polyklonal

Konjugat

  • 23
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MMP17 Antikörper ist unkonjugiert

Applikation

  • 46
  • 25
  • 19
  • 13
  • 13
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Spezifität

    This antibody reacts to MMP17.

    Aufreinigung

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MMP17.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

    Andere Bezeichnung

    MMP-17

    Hintergrund

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP17 is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.Synonyms: MMP17, MT4MMP, Matrix metalloproteinase-17, Membrane-type matrix metalloproteinase 4

    Gen-ID

    4326, 5874

    UniProt

    Q9ULZ9
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