MMP14 Antikörper (N-Term)

Produktnummer ABIN358687

Produktdetails anti-MMP14 Antikörper

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to MMP14.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP14.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Andere Bezeichnung: MMP-14 (MMP14 Produkte)

Synonyme: MMP1 antikoerper, MMP-14 antikoerper, MMP-X1 antikoerper, MT-MMP antikoerper, MT-MMP 1 antikoerper, MT1-MMP antikoerper, MT1MMP antikoerper, MTMMP1 antikoerper, mmp-x1 antikoerper, mt1-mmp antikoerper, mtmmp1 antikoerper, AI325305 antikoerper, MT-MMP-1 antikoerper, sabe antikoerper, Mt1-mmp antikoerper, MT-MMPbeta antikoerper, cb386 antikoerper, sb:cb386 antikoerper, wu:fb72b09 antikoerper, mmp14 antikoerper, matrix metallopeptidase 14 antikoerper, matrix metallopeptidase 14 (membrane-inserted) antikoerper, matrix metallopeptidase 14b (membrane-inserted) antikoerper, matrix metallopeptidase 14a (membrane-inserted) antikoerper, matrix metallopeptidase 14 L homeolog antikoerper, MMP14 antikoerper, mmp14 antikoerper, Mmp14 antikoerper, mmp14b antikoerper, mmp14a antikoerper, mmp14.L antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.Synonyms: MMP-X1, MMP14, Matrix metalloproteinase-14, Membrane-type-1 matrix metalloproteinase

Gen-ID: 4323, 9606

UniProt: P50281

Pathways: Autophagie