Cadherin 5 Antikörper (N-Term)

Produktnummer ABIN357862

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cadherin 5 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cadherin 5 Antikörper (N-Term) (ABIN357862)

Target: Cadherin 5 (CDH5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Cadherin 5 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects VE Cadherin (CD144/CDH5) (N-term).

Aufreinigung: Protein A Chromatography followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the N-term of human CDH5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: CD144 / Cadherin-5

Hintergrund: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.Synonyms: 7B4 antigen, CDH5, VE-Cadherin, Vascular endothelial cadherin

Molekulargewicht: 87516 Da

Gen-ID: 1003, 9606

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2