Epsin 2 Antikörper (N-Term)

Produktnummer ABIN357623

Der Kaninchen Polyklonal Anti-Epsin 2-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, Epsin 2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Epsin 2 Antikörper (N-Term) (ABIN357623)

Target: Epsin 2 (EPN2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Epsin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Epsin 2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is specific to Epsin-2 (N-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Epsin2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Epsin 2

Target: Epsin 2 (EPN2)

Andere Bezeichnung: Epsin-2

Hintergrund: Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.Synonyms: EPN2, EPS-15-interacting protein 2, KIAA1065

Molekulargewicht: 68553 Da

Gen-ID: 22905, 9606

UniProt: O95208

Pathways: EGFR Downregulation