Epsin 2 Antikörper (N-Term)

Produktnummer ABIN388977

Produktdetails anti-Epsin 2 Antikörper

Target: Epsin 2 (EPN2)

Bindungsspezifität: AA 6-36, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Epsin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Epsin2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human Epsin2.

Klon: RB4610

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Epsin 2 Antikörper (ABIN388977)

Bhattacharyya, Rainey, Arya, Mohapatra, Mushtaq, Dutta, George, Storck, McComb, Muirhead, Todd, Gould, Datta, Gelineau-van Waes, Band, Band: "Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development." in: Scientific reports, Vol. 6, pp. 20727, (2016) (PubMed).

Details zu Epsin 2

Target: Epsin 2 (EPN2)

Andere Bezeichnung: Epsin2 (EPN2 Produkte)

Synonyme: CG13853 antikoerper, CG13854 antikoerper, CG31170 antikoerper, CG31285 antikoerper, CG42250 antikoerper, Dmel\\CG42250 antikoerper, Dmel_CG31170 antikoerper, Dmel_CG31285 antikoerper, Epsin antikoerper, LqfR antikoerper, XII-10 antikoerper, epsin antikoerper, epsin-like antikoerper, epsin02 antikoerper, epsinR antikoerper, l(3)03685 antikoerper, l(3)A9 antikoerper, l(3)SG62 antikoerper, l(3)XII-10 antikoerper, l(3)dsl-9 antikoerper, l(3)dsl9 antikoerper, EHB21 antikoerper, 9530051D10Rik antikoerper, AA536924 antikoerper, Ibp2 antikoerper, epsin-2 antikoerper, liquid facets-Related antikoerper, epsin 2 antikoerper, epsin-2 antikoerper, Epsin 2 antikoerper, epsin 2 S homeolog antikoerper, lqfR antikoerper, EPN2 antikoerper, EDI_326810 antikoerper, EDI_044850 antikoerper, Bm1_38210 antikoerper, EHI_104950 antikoerper, epn2 antikoerper, Epn2 antikoerper, epn2.S antikoerper

Hintergrund: Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

Molekulargewicht: 68482

Gen-ID: 22905

NCBI Accession: NP_001096134, NP_055779, NP_683723

UniProt: O95208

Pathways: EGFR Downregulation