Ubiquilin 2 Antikörper (N-Term)

Produktnummer ABIN357609

Dieses Anti-Ubiquilin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ubiquilin 2 in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für Ubiquilin 2 Antikörper (N-Term) (ABIN357609)

Target: Ubiquilin 2 (UBQLN2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ubiquilin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Ubiquilin 2 Antikörper

Bindungsspezifität: AA 28-57, N-Term

Spezifität: This antibody is specific to Ubiquilin-2 (UBQLN2/DSK2) (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide between 28~57 amino acids from the N-terminal region of Human Dsk2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Ubiquilin 2

Target: Ubiquilin 2 (UBQLN2)

Andere Bezeichnung: Ubiquilin-2 (UBQLN2)

Hintergrund: Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome, it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.Synonyms: Chap1, DA41, DSK2 homolog, HRIHFB2157, N4BP4, PLIC-1, PLIC-2, PLIC1, PLIC2, Protein linking IAP with cytoskeleton 2, UBQLN1, UBQLN2, Ubiquitin-like product Chap1/Dsk2

Gen-ID: 29978, 9606

UniProt: Q9UHD9