CD73 Antikörper (C-Term)

Produktnummer ABIN357390

Produktdetails anti-CD73 Antikörper

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD73 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects CD73 (C-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human NT5E.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CD73

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Andere Bezeichnung: CD73 (NT5E Produkte)

Synonyme: CALJA antikoerper, CD73 antikoerper, E5NT antikoerper, NT antikoerper, NT5 antikoerper, NTE antikoerper, eN antikoerper, eNT antikoerper, zgc:63784 antikoerper, NT5E antikoerper, MGC114869 antikoerper, PSPTO2277 antikoerper, 2210401F01Rik antikoerper, AI447961 antikoerper, Nt5 antikoerper, 5'-nucleotidase ecto antikoerper, 5'-nucleotidase, ecto (CD73) antikoerper, 5'-nucleotidase antikoerper, 5' nucleotidase, ecto antikoerper, NT5E antikoerper, nt5e antikoerper, nt5e.S antikoerper, PSPTO_2277 antikoerper, CBU_1233 antikoerper, MCA1322 antikoerper, Nt5e antikoerper

Hintergrund: Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70 kD subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5E occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. It is not known whether the different enzymes are coded by different genes or result from different posttranslational modifications of a single coding sequence.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE

Molekulargewicht: 63367 Da

Gen-ID: 4907, 9606

UniProt: P21589

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process