URI1 Antikörper (C-Term)

Produktnummer ABIN357308

Der Kaninchen Polyklonal anti-URI1 Antikörper wird verwendet zum Nachweis von URI1 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für URI1 Antikörper (C-Term) (ABIN357308)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser URI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-URI1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human RMP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 250 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Andere Bezeichnung: RMP

Hintergrund: The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.Synonyms: C19orf2, NNX3, Protein NNX3, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein, URI, Unconventional prefoldin RPB5 interactor

Molekulargewicht: 56764 Da

Gen-ID: 8725, 9606

UniProt: O94763