URI1 Antikörper (C-Term)

Produktnummer ABIN388684

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch URI1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für URI1 Antikörper (C-Term) (ABIN388684)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser URI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB9809

Produktdetails anti-URI1 Antikörper

Bindungsspezifität: AA 347-376, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This RMP (URI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human RMP (URI).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Andere Bezeichnung: RMP (URI)

Hintergrund: The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 59832

Gen-ID: 8725

NCBI Accession: NP_001239570, NP_003787

UniProt: O94763