GJA3 Antikörper (N-Term)

Produktnummer ABIN357087

Dieses Anti-GJA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GJA3 in IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für GJA3 Antikörper (N-Term) (ABIN357087)

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJA3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GJA3 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects GJA3 at N-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human GJA3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu GJA3

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Andere Bezeichnung: GJA3 / Cx46

Hintergrund: GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract.Synonyms: Connexin-46, Gap junction alpha-3 protein

Molekulargewicht: 47296 Da

Gen-ID: 2700, 9606

UniProt: Q9Y6H8