Cadherin 12 Antikörper (N-Term)

Produktnummer ABIN356987

Der Kaninchen Polyklonal Anti-Cadherin 12-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, Cadherin 12 in Proben von Human zu detektieren.

Kurzübersicht für Cadherin 12 Antikörper (N-Term) (ABIN356987)

Target: Cadherin 12

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Cadherin 12 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects CDH12 at N-term.

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CDH12

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu Cadherin 12

Target: Cadherin 12

Andere Bezeichnung: Cadherin-12

Hintergrund: CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.Synonyms: Brain cadherin, CDH12, N-Cadherin 2, Neural type cadherin 2

Molekulargewicht: 88351 Da

Gen-ID: 1010, 9606

UniProt: P55289