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BCL2A1 Antikörper (BH3 Domain, N-Term)

BCL2A1 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356809
  • Target Alle BCL2A1 Antikörper anzeigen
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    BH3 Domain, N-Term
    Reaktivität
    • 49
    • 20
    • 12
    • 2
    • 2
    • 1
    Human
    Wirt
    • 46
    • 3
    • 1
    Kaninchen
    Klonalität
    • 39
    • 11
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser BCL2A1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 22
    • 15
    • 8
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to BCL2A1 (BH3 Domain).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody was developed against a synthetic peptide selected from the N-terminal region of human BCL2-related protein A1, within the BH3 domain.
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Abstract
    BCL2A1 Produkte
    Synonyme
    ACC-1 antikoerper, ACC-2 antikoerper, BCL2L5 antikoerper, BFL1 antikoerper, GRS antikoerper, HBPA1 antikoerper, Bcl2a1d antikoerper, BCL2A1 antikoerper, BCL2 related protein A1 antikoerper, BCL2-related protein A1 antikoerper, BCL2A1 antikoerper, Bcl2a1 antikoerper
    Hintergrund
    Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1
    Gen-ID
    597, 9606
    UniProt
    Q16548
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