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NEDD8 Antikörper (N-Term)

NEDD8 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356744
  • Target Alle NEDD8 Antikörper anzeigen
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 66
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 63
    • 4
    • 4
    Kaninchen
    Klonalität
    • 59
    • 12
    Polyklonal
    Konjugat
    • 30
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEDD8 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 27
    • 27
    • 13
    • 13
    • 12
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to NEDD8 (N-term).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NEDD8.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NEDD8 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Andere Bezeichnung
    NEDD8 (NEDD8 Produkte)
    Synonyme
    NEDD-8 antikoerper, Rub1 antikoerper, CG10679 antikoerper, Dmel\\CG10679 antikoerper, NEDD8 antikoerper, dNEDD8 antikoerper, nedd8 antikoerper, ubiquitin antikoerper, si:zc14a17.5 antikoerper, GB17785 antikoerper, DDBDRAFT_0218116 antikoerper, DDBDRAFT_0238041 antikoerper, DDB_0218116 antikoerper, DDB_0238041 antikoerper, nedd8.S antikoerper, neural precursor cell expressed, developmentally down-regulated 8 antikoerper, neural precursor cell expressed, developmentally down-regulated gene 8 antikoerper, CG10679 gene product from transcript CG10679-RB antikoerper, Nedd8 antikoerper, ubiquitin-like protein Nedd8 antikoerper, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antikoerper, NEDD8 antikoerper, Nedd8 antikoerper, nedd8 antikoerper, nedd8.L antikoerper
    Hintergrund
    NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Synonyms: Neural precursor cell expressed developmentally down-regulated protein 8
    Gen-ID
    4738, 9606
    UniProt
    Q15843
    Pathways
    Ubiquitin Proteasome Pathway
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