KDM2A Antikörper
Kurzübersicht für KDM2A Antikörper (ABIN356581)
Target
Alle KDM2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody is specific to JHDM1a/FBXL11 (Center). Predicted to cross react with Mouse (100 % Antigen Homology).
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Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center of human JHDM1a/FBXL11.
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemsitry: 1/10approx. 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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Andere Bezeichnung
- KDM2A / FBXL11
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Hintergrund
- JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.Synonyms: CXXC-type zinc finger protein 8, CXXC8, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL7, JHDM1A, KIAA1004, Lilina, Lysine-specific demethylase 2A, [Histone-H3]-lysine-36 demethylase 1A
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Gen-ID
- 22992, 9606
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UniProt
- Q9Y2K7
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Pathways
- Warburg Effekt
Target
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