Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DNMT3L Antikörper (C-Term)

This anti-DNMT3L antibody (ABIN356577) is a Rabbit Polyclonal antibody detecting DNMT3L in WB, IHC (p), EIA. Suitable for Human.
Produktnummer ABIN356577

Kurzübersicht für DNMT3L Antikörper (C-Term) (ABIN356577)

Target

Alle DNMT3L (TRDMT1) Antikörper anzeigen
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Reaktivität

  • 73
  • 19
  • 4
Human

Wirt

  • 69
  • 12
Kaninchen

Klonalität

  • 71
  • 10
Polyklonal

Konjugat

  • 38
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DNMT3L Antikörper ist unkonjugiert

Applikation

  • 65
  • 36
  • 17
  • 13
  • 13
  • 7
  • 7
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 388-417, C-Term

    Spezifität

    This antibody is specific to Dnmt3L (C-term).

    Aufreinigung

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388~417 amino acids from the C-terminal region of Human Dnmt3L. Genename: DNMT3L

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western Bot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    Andere Bezeichnung

    DNMT3L

    Hintergrund

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined.Synonyms: DNA (cytosine-5)-methyltransferase 3-like

    Gen-ID

    29947, 9606

    UniProt

    Q9UJW3
Sie sind hier:
Chat with us!