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JMJD2D Antikörper (C-Term)

KDM4D Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356558
  • Target Alle JMJD2D (KDM4D) Antikörper anzeigen
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 39
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 39
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JMJD2D Antikörper ist unkonjugiert
    Applikation
    • 28
    • 23
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody will recognize JMJD2D (C-term).
    Aufreinigung
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human JMJD2D.
    Isotyp
    Ig Fraction
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    Discover our top product KDM4D Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/250-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Andere Bezeichnung
    JMJD2D / KDM4D (KDM4D Produkte)
    Synonyme
    JMJD2D antikoerper, 4932416A15 antikoerper, Jmjd2d antikoerper, KDM4D antikoerper, lysine demethylase 4D antikoerper, lysine-specific demethylase 4D antikoerper, lysine (K)-specific demethylase 4D antikoerper, KDM4D antikoerper, LOC524768 antikoerper, Kdm4d antikoerper, LOC617971 antikoerper, LOC100067461 antikoerper, LOC698455 antikoerper, LOC100514356 antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: JHDM3D, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D, Lysine-specific demethylase 4D
    Gen-ID
    55693
    NCBI Accession
    NP_060509
    UniProt
    Q6B0I6
    Pathways
    Warburg Effekt
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