Thyroglobulin Antikörper

Produktnummer ABIN356334

Dieses Anti-Thyroglobulin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Thyroglobulin in FACS, IHC (p), IF und IHC (fro). Geeignet für Human.

Kurzübersicht für Thyroglobulin Antikörper (ABIN356334)

Target: Thyroglobulin (TG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thyroglobulin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: TG221

Produktdetails anti-Thyroglobulin Antikörper

Spezifität: This antibody Tg is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of Tg in metastatic lesion establishes thyroid origin of tumor.
Cellular Localization: Cytoplasmic.

Produktmerkmale: Synonyms: Thyreoglobulin, TGN

Aufreinigung: Purified

Immunogen: Purified human Thyroglobulin. Remarks: Molecular weight of antigen: 330 kDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. Immunofluorescence. Recommended Positive Control: Human thyroid.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch

Haltbarkeit: 12 months

Details zu Thyroglobulin

Target: Thyroglobulin (TG)

Hintergrund: Thyroglobulin (Tg) is a 660 kDa dimeric protein produced by and used by entirely within thyroid gland. Tg is used by the thyroid gland to produce the thyroid hormone thyroxine (T4) and triiodothyronine (T3). Tg is produced by the thyroid epithelial cells, called thyrocytes, which form spherical follicles. Tg is stored in the follicle lumen. Tg levels in the blood can be used as markers for certain kind of thyroid cancer. Tg levels are also elevated in Graves disease.Synonyms: TGN, Thyreoglobulin

Gen-ID: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis