PERP Antikörper (C-Term)
Kurzübersicht für PERP Antikörper (C-Term) (ABIN356105)
Target
Alle PERP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human
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Aufreinigung
- affinity purified
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Immunogen
- Synthetic peptide corresponding to AA near the carboxy terminus of human PERP, which differ from the mouse sequence by three AA (7-9).
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- -20 °C
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- PERP (TP53 Apoptosis Effector (PERP))
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Andere Bezeichnung
- PERP/TP53 Apoptosis Effector Protein
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Hintergrund
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP (TP53 Apoptosis Effector) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
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Pathways
- Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity
Target
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