c-FOS Antikörper

Produktnummer ABIN350206

Dieses Schaf Polyklonal-Antikörper erkennt spezifisch c-FOS in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für c-FOS Antikörper (ABIN350206)

Target: c-FOS (c-Fos) (c-Fos)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser c-FOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-c-FOS Antikörper

Verwendungszweck: Sheep antibody to cFos

Spezifität: Specific for cFos.

Kreuzreaktivität: Human, Marmoset, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from human cFos protein conjugated to blue carrier protein has been used as the antigen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Andere Bezeichnung: cFos

Hintergrund: FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli including growth factors cytokines neurotransmitters polypeptide hormones stress and cell injury. SIMILARITY: Belongs to the bZIP family. Fos subfamily SIMILARITY: Contains 1 bZIP domain

UniProt: P01100

Pathways: S100 Proteine