Ubiquitin Antikörper (N-Term)

Produktnummer ABIN350073

Dieses Anti-Ubiquitin-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von Ubiquitin in WB, IHC, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für Ubiquitin Antikörper (N-Term) (ABIN350073)

Target: Ubiquitin (Ub)

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Ubiquitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Ubiquitin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Goat antibody to Ubiquitin

Spezifität: Specific for AUP1.

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic pentamer-peptide from the n-terminal region of human ancient ubiquitous protein 1 (AUP1) conjugated to blue carrier protein was used as the antigen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. This antibody works nicely in both paraffin,frozen sections. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Ubiquitin

Target: Ubiquitin (Ub)

Andere Bezeichnung: Ubiquitin

Hintergrund: This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

UniProt: A1L134

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway