A synthetic peptide from human transmembrane protein 166 (TM166 TMEM166) conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
FAM176A
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handhabung
Avoid freeze and thaw cycles.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit
12 months
Target
TMEM166 (FAM176A)
(Family with Sequence Similarity 176, Member A (FAM176A))
Andere Bezeichnung
TMEM166
Hintergrund
FUNCTION: Acts as a regulator of programmed cell death mediating both autophagy and apoptosis. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane, Single-pass membrane protein. Lysosome membrane, Single-pass membrane protein. TISSUE SPECIFICITY: Expressed in lung kidney liver pancreas placenta but not in heart and skeletal muscle.