CENPQ Antikörper
Kurzübersicht für CENPQ Antikörper (ABIN349636)
Target
Alle CENPQ Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Hersteller Produkt- Nr.
- 200-401-b48
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Hersteller
- Rockland
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Verwendungszweck
- CENP-Q Antibody
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Kreuzreaktivität (Details)
- This antibody is specific for human CENP-Q protein.
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Produktmerkmale
- Synonyms: rabbit anti-CENP-Q Antibody, CenpQ, centromere protein Q, CENP Q
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Aufreinigung
- This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.
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Sterilität
- Sterile filtered
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Immunogen
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Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein.
Immunogen Type: Recombinant Protein
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Isotyp
- IgG
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Applikationshinweise
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Application Note: This protein A purified antibody has been tested for use in ELISA, immunofluorescence microscopy and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 26-31 kDa in size corresponding to human CENP-Q by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:100 - 1:500
ELISA Dilution: 1:5,000 1:20,000
IF Microscopy Dilution: User Optimized
Other: User Optimized
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.15 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Haltbarkeit
- 12 months
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- CENPQ (Centromere Protein Q (CENPQ))
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Andere Bezeichnung
- CENPQ
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Hintergrund
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.
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Gen-ID
- 55166, 40068061
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UniProt
- Q7L2Z9
Target
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