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CENPQ Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CENPQ in WB, ELISA, IF, FM und MA. Er zeigt eine Reaktivität gegenüber Human.
Rockland
Produktnummer ABIN349636
Hersteller Produkt- Nr.: 200-401-b48

Kurzübersicht für CENPQ Antikörper (ABIN349636)

Target

Alle CENPQ Antikörper anzeigen
CENPQ (Centromere Protein Q (CENPQ))

Reaktivität

  • 6
  • 1
  • 1
Human

Wirt

  • 6
  • 1
Kaninchen

Klonalität

  • 6
  • 1
Polyklonal

Konjugat

  • 7
Dieser CENPQ Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM), Multiplex Assay (MA)
  • Hersteller Produkt- Nr.

    200-401-b48

    Hersteller

    Rockland

    Verwendungszweck

    CENP-Q Antibody

    Kreuzreaktivität (Details)

    This antibody is specific for human CENP-Q protein.

    Produktmerkmale

    Synonyms: rabbit anti-CENP-Q Antibody, CenpQ, centromere protein Q, CENP Q

    Aufreinigung

    This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein.

    Immunogen Type: Recombinant Protein

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This protein A purified antibody has been tested for use in ELISA, immunofluorescence microscopy and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 26-31 kDa in size corresponding to human CENP-Q by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:100 - 1:500

    ELISA Dilution: 1:5,000 1:20,000

    IF Microscopy Dilution: User Optimized

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.15 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Target

    CENPQ (Centromere Protein Q (CENPQ))

    Andere Bezeichnung

    CENPQ

    Hintergrund

    Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.

    Gen-ID

    55166, 40068061

    UniProt

    Q7L2Z9
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