TTC3 Antikörper (N-Term)
Kurzübersicht für TTC3 Antikörper (N-Term) (ABIN347721)
Target
Alle TTC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Reacts with human E3 ubiquitin-protein ligase TTC3
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Aufreinigung
- Antiserum
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Immunogen
- Synthetic peptide derived from Cter domain of human TTC3
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Isotyp
- IgG
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Must be reconstituted in distilled water.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Haltbarkeit
- 24 months
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- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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Andere Bezeichnung
- E3 ubiquitin-protein ligase TTC3
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Hintergrund
- E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
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UniProt
- P53804
Target
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