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TTC3 Antikörper (N-Term)

This anti-TTC3 antibody (ABIN347721) is a Rabbit Polyclonal antibody detecting TTC3 in ELISA, WB, IF. Suitable for Human.
Produktnummer ABIN347721

Kurzübersicht für TTC3 Antikörper (N-Term) (ABIN347721)

Target

Alle TTC3 Antikörper anzeigen
TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

Reaktivität

  • 4
  • 4
  • 3
Human

Wirt

  • 5
  • 2
Kaninchen

Klonalität

  • 6
  • 1
Polyklonal

Konjugat

  • 5
  • 1
  • 1
Dieser TTC3 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 3
    • 2
    • 1
    N-Term

    Spezifität

    Reacts with human E3 ubiquitin-protein ligase TTC3

    Aufreinigung

    Antiserum

    Immunogen

    Synthetic peptide derived from Cter domain of human TTC3

    Isotyp

    IgG
  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    IF(1:100 - 1:500) WB(1:500 - 1:5000)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Must be reconstituted in distilled water.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    Haltbarkeit

    24 months
  • Target

    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

    Andere Bezeichnung

    E3 ubiquitin-protein ligase TTC3

    Hintergrund

    E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

    UniProt

    P53804
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