TTC3 Antikörper (N-Term)
Kurzübersicht für TTC3 Antikörper (N-Term) (ABIN347721)
Target
Alle TTC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- N-Term
- 
                                            Spezifität
- Reacts with human E3 ubiquitin-protein ligase TTC3
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                                            Aufreinigung
- Antiserum
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                                            Immunogen
- Synthetic peptide derived from Cter domain of human TTC3
- 
                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
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                        Working dilution: Optimal dilution should be determined by the end user. 
 The following are guidelines only :
 IF(1:100 - 1:500) WB(1:500 - 1:5000)
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Lyophilized
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                                            Rekonstitution
- Must be reconstituted in distilled water.
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                                            Lagerung
- 4 °C/-20 °C
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                                            Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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                                            Haltbarkeit
- 24 months
 
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    - TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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                                            Andere Bezeichnung
- E3 ubiquitin-protein ligase TTC3
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                                            Hintergrund
- E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
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                                            UniProt
- P53804
 Target
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