AMBRA1 Antikörper (N-Term)
Kurzübersicht für AMBRA1 Antikörper (N-Term) (ABIN347117)
Target
Alle AMBRA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Reacts with mouse 120 kDa Ambra1 protein
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Kreuzreaktivität
- Ratte (Rattus)
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Kreuzreaktivität (Details)
- Cross reacts with human and rat protein.
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Aufreinigung
- Antiserum
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Immunogen
- Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
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Isotyp
- IgG
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Must be reconstituted in distilled water.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Haltbarkeit
- 24 months
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Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).
: "
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Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
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- AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))
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Andere Bezeichnung
- Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1)
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Hintergrund
- Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation
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Gen-ID
- 55626
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UniProt
- Q9C0C7
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Pathways
- Autophagie
Target
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