HMGB1 Antikörper (meLys42, N-Term)

Produktnummer ABIN347109

Dieses Anti-HMGB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMGB1 in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für HMGB1 Antikörper (meLys42, N-Term) (ABIN347109)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-HMGB1 Antikörper

Bindungsspezifität: meLys42, N-Term

Spezifität: Reacts with HMGB1 methylated on Lysine 42 from human neutrophils

Kreuzreaktivität (Details): Not tested in other species. May cross react with a wide range of species due to sequence homology.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC1:100 - 1:1000 WB1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung: HMGB1

Hintergrund: HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.

Gen-ID: 3146

UniProt: P09429

Pathways: p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome