MAF Antikörper

Produktnummer ABIN346926

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAF in WB, ELISA, IHC und IEM. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MAF Antikörper (ABIN346926)

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoelectron Microscopy (IEM)

Produktdetails anti-MAF Antikörper

Spezifität: Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line

Aufreinigung: Antiserum

Immunogen: Maf-GST fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu MAF

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Andere Bezeichnung: Transcription Factor Maf

Hintergrund: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

NCBI Accession: NP_001026974

UniProt: O75444