Progesterone Receptor Antikörper (C-Term)
Kurzübersicht für Progesterone Receptor Antikörper (C-Term) (ABIN342255)
Target
Alle Progesterone Receptor (PGR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Spezifität
- Recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.
-
Aufreinigung
- Protein G purified
-
Immunogen
-
6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.
Type of Immunogen: Fusion protein -
Isotyp
- IgG2a
-
-
-
-
Applikationshinweise
- Approved: WB (1 - 5 μg/mL)
-
Kommentare
-
Target Species of Antibody: Human
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- PBS, pH 7.4
-
Handhabung
- Avoid freeze/thaw cycles.
-
Lagerung
- -80 °C
-
Informationen zur Lagerung
- Store at -70°C, avoid freeze/thaw cycles.
-
-
- Progesterone Receptor (PGR)
-
Andere Bezeichnung
- PGR/PR/Progesterone Receptor
-
Hintergrund
-
Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: PGR, NR3C3, PR, Progesterone receptor -
Gen-ID
- 5241
-
UniProt
- P06401
-
Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Target
-