Smooth Muscle Actin Antikörper

Produktnummer ABIN336852

Dieser Anti-Smooth Muscle Actin Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von Smooth Muscle Actin in IHC und IHC (p). Geeignet für Human, Ratte, Maus, Huhn, Rind (Kuh) und Pavian.

Kurzübersicht für Smooth Muscle Actin Antikörper (ABIN336852)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reaktivität: Human, Ratte, Maus, Huhn, Rind (Kuh), Pavian

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Smooth Muscle Actin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1A4

Produktdetails anti-Smooth Muscle Actin Antikörper

Spezifität: Acetyl group with N- terminal four amino acids of peptide chain of alpha smooth muscle.

Immunogen: N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at the N-terminus

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections and cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin-biotin system or polymer system, incubate 30 minutes at room temperature. Prediluted antibody is ready to be used for IHC. The optimum dilution should be determined by the individual lab. Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma. Cellular Localization: Cytoplasmic.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Andere Bezeichnung: a-Actin alpha smooth muscle

Hintergrund: Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells. Actin participates in many important cellular functions, including muscle contraction cell motility cell division and cytokinesis vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Expression of smooth muscle alpha actin is regulated by hormones and cell proliferation and is altered by pathological conditions including onogenic transformation and atherosclerosis.

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development