CA 19-9 Antikörper
Kurzübersicht für CA 19-9 Antikörper (ABIN336849)
Target
Alle CA 19-9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts with CA 19-9 antigen. Does not cross react with CA125, CA15-3, CEA. Epitope: Carbohydrate moiety.
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Immunogen
- Mucins from ovarian cyst
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections, the conc. antibodies can be diluted 1:50 -1:100 using polymer or streptavidin -biotin system for 30 mins at room temperature. The Prediluted antibodies are ready to use. The optimum dilution should be determined by the individual lab. Positive Control: Human colon, stomach, pancreas, intestine, breast carcinomas. Cellular Localization: Cytoplasmic.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
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Andere Bezeichnung
- CA 19-9
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Hintergrund
- The CA 19-9 antigen is a monosialosyl Le (a) blood group antigen which has been shown to be a useful-associated antigen for the diagnosis of gastrointestinal cancers. This antigen is known to be a ligand for the cell adhesion molecule called ELAM-1 (E-selectin, endothelial cell leukocyte adhesion molecule-1, which is present on cytokine-activated human endothelial cells. Selectin GMP-140 (CD62,PADGEM) binds to sialosyl Le (a) and sulfated glycans modulate this binding.
Target
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