Rekombinanter CA 19-9 Antikörper

Produktnummer ABIN6936552

Der Kaninchen Monoklonal anti-CA 19-9 Antikörper wird verwendet zum Nachweis von CA 19-9 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter CA 19-9 Antikörper (ABIN6936552)

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CA 19-9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: CA19-9-1390R

Produktdetails anti-CA 19-9 Antikörper

Verwendungszweck: Recombinant CA19-9/Sialyl Lewisa (GI Tumor Marker) Antibody

Spezifität: CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Aufreinigung: 200ug/ml of Ab Purified by Protein A column.

Immunogen: Purified human CA19-9 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Stomach or Colon Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (5-10 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CA 19-9

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Andere Bezeichnung: CA19-9/Sialyl Lewisa (GI Tumor Marker)

Hintergrund:

CA19.9, CA199, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a

Stomach or Colon Carcinoma.

Molekulargewicht: 400kDa