14-3-3 theta Antikörper (N-Term)
Kurzübersicht für 14-3-3 theta Antikörper (N-Term) (ABIN336110)
Target
Alle 14-3-3 theta (YWHAQ) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-245, N-Term
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Spezifität
- The antibody recognizes Human 14-3-3 protein theta (tau). Other species not tested.
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Produktmerkmale
- Synonyms: 14-3-3 protein tau, 14-3-3 protein T-cell, YWHAQ, Protein HS1
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Aufreinigung
- Protein-G affinity chromatography
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Immunogen
- Recombinant human 14-3-3 tau (aa 1-245) purified from E. coli
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Isotyp
- IgG1
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Applikationshinweise
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ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (10 μg/mL). This YWHAQ antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- 14-3-3 theta (YWHAQ)
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Andere Bezeichnung
- 14-3-3 Protein theta
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Hintergrund
- The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.Synonyms: 14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1, YWHAQ
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Gen-ID
- 10971
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UniProt
- P27348
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Pathways
- Apoptose, Myometrial Relaxation and Contraction
Target
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