Mesothelin Antikörper

Produktnummer ABIN328471

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch Mesothelin in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Mesothelin Antikörper (ABIN328471)

Target: Mesothelin (MSLN)

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Mesothelin Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Produktdetails anti-Mesothelin Antikörper

Spezifität: Recognizes human mesothelin. This antibody binds to mesothelin cleaved form which is the ~40 kDa cell membrane-associated glycosylphosphatidylinositol-linked glycoprotein. It is not expected to react with the soluble portion of the mesothelin precursor protein that is designated as the megakaryocyte potentiating factor.

Aufreinigung: Immunoaffinity purified

Immunogen: NS0-derived recombinant human mesothelin.

Type of Immunogen: Recombinant protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), Flo (2.5 μg/10 x10⁶)

Usage: Flow Cytometry: This antibody was validated for flow cytometry using Hela human cervical carcinoma cells. Use at 2.5 μg per 10e6 cells. Direct ELISA: 0.5-1.0 μg/mL with the appropriate secondary reagents to detect human Mesothelin. The detection limit for rhMesothelin is approximately 5 ng/well.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 200 μL sterile PBS

Konzentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose

Handhabung: Avoid freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Mesothelin

Target: Mesothelin (MSLN)

Andere Bezeichnung: MSLN / Mesothelin

Hintergrund: Name/Gene ID: MSLN

Synonyms: MSLN, CAK1 antigen, MPF, SMRP, Mesothelin, CAK1

Gen-ID: 10232

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process