CD13 Antikörper (PE)

Produktnummer ABIN320068

Produktdetails anti-CD13 Antikörper (PE)

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD13 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: MCA2183PE recognises mouse aminopeptidase N (APN), a cell surface protein homologous with human CD13. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150 kDa subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. Clone R3-63 has been reported to block mouse APN enzyme activity (1). Serotec recommend the use of MCA2183XZ for this purpose.

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Mouse intestinal APN

Klon: R3-63

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry Neat
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute in 0.25 mL disilled water

Konzentration: 0.1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 0.09 % Sodium Azide, 1 % Bovine Serum Albumin,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu CD13

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Andere Bezeichnung: CD13 (ANPEP Produkte)

Hintergrund: CD13 also known as Aminopeptidase N is a zinc dependent exopeptidase which cleaves amino acids from the N termini of target proteins including neuropeptides and cytokines. CD13 is expressed on all cells of the myeloid lineage as well as epithelial cells of the intestine, placenta, liver and kidney. CD13 is upregulated in a number of tumour types including lung, melanoma, thyroid and hepatocarcinoma and has been shown to correlate with poor prognosis. CD13 is a crucial molecule in tumour angiogenesis. CD13 is also the receptor for viruses from the coronavirus family.Synonyms: ANPEP, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150

Gen-ID: 16790

NCBI Accession: NP_032512

UniProt: P97449

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones