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Transferrin Receptor Antikörper

TFRC Reaktivität: Maus FACS, IP, IHC (fro) Wirt: Ratte Monoclonal YTA74-4 unconjugated
Produktnummer ABIN319606
  • Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Reaktivität
    • 211
    • 96
    • 35
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 127
    • 114
    • 37
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 180
    • 97
    • 3
    Monoklonal
    Konjugat
    • 132
    • 27
    • 24
    • 17
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Transferrin Receptor Antikörper ist unkonjugiert
    Applikation
    • 168
    • 137
    • 74
    • 69
    • 59
    • 44
    • 26
    • 26
    • 21
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody reacts with the Transferrin Receptor (TFR). Expressed on all dividing cells and can distinguish resting and activated T-cells. Immunoprecipitates a disulphide linked homodimer of 90 kDa by SDS PAGE. The antibody inhibits cell proliferation and the mixed lymphocyte response in vitro. Blocks the binding of R17 217.1.3. and R17 208.2 anti-TFR monoclonal antibodies (1,2).
    Aufreinigung
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Immunogen
    Mouse Concanavilin A activated spleen cells. Spleen cells from an immunised DA rat were fused with cells of the Y3/Ag1.2.3 rat myeloma cell line.
    Klon
    YTA74-4
    Isotyp
    IgG2a
    Top Product
    Discover our top product TFRC Primärantikörper
  • Applikationshinweise
    Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Andere Bezeichnung
    CD71 / TFRC (TFRC Produkte)
    Hintergrund
    CD71 antigen expression is low on normal resting lymphocytes and is expressed on all cells upon activation. The transferrin receptor is essential for iron transport into proliferating cells, such as mitogen-activated and alloantigen-activated lymphoblasts. The transferrin receptor is also present on early erythroid cells but is lost as reticulocytes differentiate into mature erythrocytes.Synonyms: TfR1, Transferrin receptor protein 1, p90
    Gen-ID
    22042
    NCBI Accession
    NP_035768
    UniProt
    Q62351
    Pathways
    Transition Metal Ion Homeostasis
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