Glutamate Receptor 1 Antikörper (pSer831)

Produktnummer ABIN319113

Der Kaninchen Polyklonal anti-Glutamate Receptor 1 Antikörper (ABIN319113) detektiert spezifisch Glutamate Receptor 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Huhn und Hund.

Kurzübersicht für Glutamate Receptor 1 Antikörper (pSer831) (ABIN319113)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus, Huhn, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: pSer831

Spezifität: This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: Glutamate Receptor 1 / GLUR1

Hintergrund: GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gen-ID: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signalweg