IL-2 Antikörper

Produktnummer ABIN318983

Der Kaninchen Polyklonal anti-IL-2 Antikörper wird verwendet zum Nachweis von IL-2 in Proben von Human und Affe. Er wurde validiert für WB, EIA und Func.

Kurzübersicht für IL-2 Antikörper (ABIN318983)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Produktdetails anti-IL-2 Antikörper

Immunogen: Recombinant human IL-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 5g/mL - 10g/mL. Western Blot. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 9606

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation