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RIPK2 Antikörper (N-Term)
RIPK2
Reaktivität: Human, Maus, Ratte
WB, IF, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-RIPK2 Antikörper
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Target
Alle RIPK2 Antikörper anzeigen
RIPK2
(Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
Bindungsspezifität
Alle Epitope für RIPK2 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für RIPK2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für RIPK2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für RIPK2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für RIPK2 Antikörper
Dieser RIPK2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für RIPK2 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
This antibody recognises Human RIP2 (Receptor-interacting kinase 2), a 61.2 kDa cytoplasmic protein belonging to the protein kinase superfamily.
Aufreinigung
Purified
Immunogen
A peptide corresponding to amino acids near the amino terminus of human RIP2.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 60 kDa in A431 cell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu RIPK2
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Target
RIPK2
(Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
Andere Bezeichnung
RIPK2 (RIPK2 Produkte )
Synonyme
RIPK2 antikoerper, 2210420D18Rik antikoerper, CARD3 antikoerper, CARDIAK antikoerper, CCK antikoerper, D4Bwg0615e antikoerper, RICK antikoerper, RIP2 antikoerper, GIG30 antikoerper, receptor interacting serine/threonine kinase 2 antikoerper, receptor (TNFRSF)-interacting serine-threonine kinase 2 antikoerper, receptor-interacting serine-threonine kinase 2 antikoerper, RIPK2 antikoerper, Ripk2 antikoerper
Hintergrund
RIP2, known also as RICK and CARDIAK, is a novel kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta. Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues.Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2
Gen-ID
8767
NCBI Accession
NP_003812
UniProt
O43353
Pathways
T-Zell Rezeptor Signalweg , Neurotrophin Signalübertragung , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , Toll-Like Receptors Cascades
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