This antibody recognises thymic stromal lymphopoietin receptor (TSLPR).
Aufreinigung
Antisera to human TSLP receptor were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen
A 19 amino acid peptide located near the centre of human TSLP recptor.
CRLF2
Reaktivität: Maus, Ratte
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 53 kDa in human liver tissuecell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
CRLF2
(Cytokine Receptor-Like Factor 2 (CRLF2))
Andere Bezeichnung
CRLF2
Hintergrund
TSLPR is a 42 kDa glycoprotein belonging to the type 1 cytokine receptor family. TSLPR is primarily expressed by dendritic cells and monocytes, and weakly expressed by T-cells. It is also expressed by non-haematopoietic tissues such as the heart, skeletal muscle, kidney and liver. The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor