MAP2K5 Antikörper (pSer311, pThr315)

Produktnummer ABIN318850

Produktdetails anti-MAP2K5 Antikörper

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Bindungsspezifität: pSer311, pThr315

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Huhn, Zebrafisch (Danio rerio), Xenopus laevis, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody specifically recognises 49 kDa MEK5, also known as MAP2K5, when phosphorylated at Ser311 and Thr315. Activation of MEK5 itself is regulated by upstream MAP3K3/MEKK3, and phosphorylation of MEK5 at both the Ser311 and Thr315 sites has been implicated in cell proliferation.

Aufreinigung: Purified

Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within MEK5 , which includes phoshorylated Ser311 and Thr315.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 1000, detects a band of approximately 49 kDa in rat testes cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 0.01 % Bovine Serum Albumin, 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Andere Bezeichnung: MAP2K5 (MAP2K5 Produkte)

Synonyme: Mek5 antikoerper, HsT17454 antikoerper, MAPKK5 antikoerper, MEK5 antikoerper, PRKMK5 antikoerper, AI324775 antikoerper, AI428457 antikoerper, Mapkk5 antikoerper, Prkmk5 antikoerper, fb73f02 antikoerper, wu:fb73f02 antikoerper, zgc:172137 antikoerper, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 antikoerper, ATMAP2K_ALPHA antikoerper, ATMEK5 antikoerper, ATMKK5 antikoerper, MAP KINASE KINASE 5 antikoerper, MAP kinase kinase 5 antikoerper, MAP2K_A antikoerper, mitogen activated protein kinase kinase 5 antikoerper, mitogen-activated protein kinase kinase 5 antikoerper, mitogen-activated protein kinase kinase 5 L homeolog antikoerper, MAP kinase kinase 5 antikoerper, Map2k5 antikoerper, MAP2K5 antikoerper, map2k5 antikoerper, map2k5.L antikoerper, MKK5 antikoerper

Hintergrund: MEK5 is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family, which acts as a key regulator in a mitogen-activated protein (MAP) kinase cascade, and hence growth factor-induced cellular stimulation. MEK5 exists in naturally occurring MEK5alpha and MEK5beta splice variants, the former of which is known to specifically activate/regulate MAPK7/ERK5/BMK1, whilst the latter may act as a suppressor of MAPK7 activation.Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MEK5, MKK5

Gen-ID: 5607

NCBI Accession: NP_001193733

UniProt: Q13163

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung