POMC Antikörper (N-Term)
Kurzübersicht für POMC Antikörper (N-Term) (ABIN318390)
Target
Alle POMC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-24, N-Term
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Sequenz
- SYSMEHFRWG KPVGKKRRPV KVYP
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Spezifität
- This antibody reacts to ACTH.
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Aufreinigung
- Purified Ig prepared by affinity chromatography on Protein G
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Immunogen
- Synthetic peptide corresponding to the amino acids 1-24 of ACTH conjugated to Keyhole limpet Haemocyanin.
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Isotyp
- IgG
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Applikationshinweise
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Immunohistochemistry on frozen sections: 1/100 - 1/200. Immunohistochemistry on paraffin sections: 1/100 - 1/200. ELISA: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 5.0 mg/mL
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Buffer
- Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- POMC (Proopiomelanocortin (POMC))
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Andere Bezeichnung
- POMC
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Hintergrund
- ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC
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Gen-ID
- 5443
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NCBI Accession
- NP_000930
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UniProt
- P01189
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
Target
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